THE LONGEVITY RITUAL

Understand what changes. Support how you age.

Energy. Rest. Strength. Clarity. A closer look at the biology behind how you feel—and a daily approach built around it.

Explore the biology ↓
Fine-line cell illustration with a softly shaded nucleus and peach mitochondria
01 / INSIDE THE CELLFollow the NMN pathway ↗

THE CHANGES YOU NOTICE

How you feel has a deeper story.

Some changes arrive quietly. Understanding the systems underneath them gives your daily routine a clearer purpose.

Concept illustration: Energy that feels less consistent.
CONTEXT ILLUSTRATION · NOT STUDY DATA
01

Energy that feels less consistent.

Look closer at cellular energy production.

Concept illustration: Sleep that feels less restorative.
CONTEXT ILLUSTRATION · NOT STUDY DATA
02

Sleep that feels less restorative.

Explore the signals that coordinate rest.

Concept illustration: Strength that needs more attention.
CONTEXT ILLUSTRATION · NOT STUDY DATA
03

Strength that needs more attention.

Understand how muscle is maintained.

Concept illustration: Clarity you want to hold onto.
CONTEXT ILLUSTRATION · NOT STUDY DATA
04

Clarity you want to hold onto.

Consider the systems supporting cognition.

These experiences have many possible causes. They are not a diagnosis or an inevitable part of aging.

01 / CELLULAR ENERGY

Before you feel energy, your cells make it.

Mitochondria help turn energy from nutrients into ATP: a molecule cells use to power their work.

Human research has found age-associated changes in skeletal-muscle mitochondrial function. Activity, health and individual biology also matter.

HUMAN BIOLOGY · SHORT ET AL., 2005146 adults · Age-associated differences in muscle ATP production ↗

INSIDE THE CELL / SCROLL TO EXPLORE

Where NMN
comes in.

Inside the cell: NMN, NAD+ and mitochondrial energy metabolism One illustrative cellular uptake route: extracellular NMN becomes NR, enters a cell, and is rebuilt as NMN. NMNAT uses NMN and ATP to make NAD+. NAD+ enters a mitochondrion; a magnified interior shows NAD+ accepting electrons to become NADH, delivering electrons to the respiratory chain and being recycled. The proton gradient supports ATP synthase. This is not a complete oral absorption pathway or a product result. NAD⁺ import Mitochondria Cell membrane P NMNATATP used · PPi released NMN NAD⁺ INSIDE THE MITOCHONDRION NAD⁺ accepts electrons. NAD⁺NADH A reusable electron carrier NAD⁺ 2e⁻ Respiratory chain H⁺ ATP synthase Inner membrane ATPATP
  1. 01 / CELLULAR UPTAKE

    A route into the cell.

    In one studied route, NMN becomes NR before entering a cell. Inside, NRK enzymes rebuild NMN.

  2. 02 / MAKING NAD⁺

    From precursor to coenzyme.

    NMNAT enzymes use NMN and ATP to make NAD⁺. Follow the molecule as its role changes.

  3. 03 / A CLOSER LOOK

    Inside the mitochondrion.

    NAD⁺ can enter mitochondria through a transporter. Here, it accepts electrons from nutrient metabolism to become NADH.

  4. 04 / TRANSFER & RECYCLE

    Carry. Deliver. Repeat.

    NADH supplies electrons to the respiratory chain and returns to NAD⁺. The chain builds a proton gradient that helps drive ATP production.

01 / CELLULAR UPTAKESCROLL TO CONTINUE ↓

Conceptual cellular pathway, not a measured product result. Uptake via NR is one studied route; oral digestion, other routes and tissue differences are not shown. Timing, scale and particle counts are illustrative. Explore the sources ↗

FROM MECHANISM TO HUMAN RESEARCH

What has NMN research measured?

The pathway explains the rationale. Human studies ask a separate question: what changes after supplementation?

THE MORNING RITUALHaroutine Advanced Liposomal NMN box and packet

CELLULAR ENERGY / OUR STARTING POINT

A formulation with a clear purpose.

Advanced Liposomal NMN

Built around NAD+ metabolism, with complementary ingredients selected for the morning formula.

500 mg

Liposomal NMN

A precursor for NAD+ synthesis.

100 mg

Liposomal CoQ10

A coenzyme involved in electron transport.

1 mg

Spermidine

Included in the formula’s cellular-maintenance approach.

Explore Advanced Liposomal NMN ↗

Ingredient roles explain formulation rationale. Results from other preparations do not establish results for this formula.

02 / SLEEP & REGULATION

Rest is not a pause.
It is active biology.

While you sleep, the body and brain move through a repeating pattern of recovery and processing.

Time matters. So does the rhythm within it. Deep sleep and REM have different roles—and both belong in the story of aging well.

7–9 hGeneral adult sleep range*
4–6Cycles in a typical night
The biology of sleep · NHLBI ↗

FOLLOW A NIGHT / SCROLL TO EXPLORE

A full night.
Different kinds of rest.

EXAMPLE WINDOW · 11 PM — 7 AM
An illustrative night on a 24-hour clockAn illustrative 11 PM to 7 AM night. Blue bands show deep sleep more prominent earlier; peach bands show REM periods longer later. Stages recur. Timing and interruptions are illustrative, not a prescribed schedule or product result.MIDNIGHT6 AMNOON6 PM11:00 PMEXAMPLE SLEEP WINDOWREPEATEDAWAKENINGS
24-HOUR CLOCK · EXAMPLE SLEEP WINDOWSleep windowDeepREMPossible waking
  1. LIGHT SLEEP / THE TRANSITION

    The night begins
    by slowing down.

    As you move into non-REM sleep, breathing and heart rate slow. Light sleep leads into deeper stages and returns between them.

    Each cycle matters. The stages repeat, rather than happening just once.

    Sleep science ↗
  2. DEEP SLEEP / PHYSICAL RECOVERY

    Recovery has
    a deeper phase.

    Deep sleep is associated with growth-hormone release involved in tissue repair. It is usually more prominent earlier in the night.

    Watch the blue sections: deeper periods are longer toward the beginning.

    Sleep science ↗
  3. REM / MEMORY & LEARNING

    An active brain.
    A different kind of rest.

    REM is linked to learning and memory. Its periods generally lengthen later in the night—another reason the full night matters.

    Watch the peach sections. Non-REM sleep also contributes to memory.

    Sleep science ↗
  4. CONTINUITY / PROTECT THE PATTERN

    Enough hours.
    Room for the cycles.

    Repeated waking or cutting the night short can interrupt the pattern. Daytime tiredness despite enough sleep can signal poor sleep quality.

    Brief awakenings between cycles can be normal. The extra markers illustrate possible disruptions.

    Sleep science ↗
SCROLL THROUGH THE NIGHT ↓

Illustrative timing, not an ideal-night score or a product result. Stages and cycles vary. Deep sleep and REM recur across the night.

Recommendations, aging & sources

Adult guidance varies by age: CDC recommends at least 7 hours for ages 18–60, 7–9 hours for ages 61–64 and 7–8 hours for ages 65+. The clock uses an example 11 PM–7 AM window, not a prescribed bedtime. Persistent sleep problems merit individual assessment.

WHEN THE RHYTHM CHANGES / MIDLIFE CONTEXT

Sleep changes
have a deeper context.

During perimenopause and menopause, changing hormone levels can bring hot flashes and night sweats that disturb sleep. The same hours in bed may begin to feel different.

Sleep changes can also have other causes. Recognizing the pattern helps make the next conversation more useful.

Menopause & sleep · NIH ↗

Changing hormones

Patterns shift through the transition.

Nighttime temperature

Night sweats can interrupt rest.

Your life stage belongs in the protocol.

Persistent sleep problems deserve individual assessment. Rest + Restore is not a treatment for menopause or a replacement for care.

FROM BIOLOGY TO EVIDENCE

What has actually
been studied?

The sleep cycle explains the biology. Ingredient trials ask a narrower question: can a specific intervention change a measured sleep outcome?

Concept illustration, not study data
MAGNESIUM / RANDOMIZED CONTROLLED TRIAL

A modest change
in reported insomnia symptoms.

In adults reporting poor sleep, magnesium bisglycinate produced a small improvement in Insomnia Severity Index scores versus placebo after four weeks.

155adults enrolled
250 mgelemental magnesium/day
4 weeksduration

Small effect (d = 0.2). Questionnaire outcomes; no objective deep-sleep or REM measurement. This studied bisglycinate, not the finished Haroutine blend.

Schuster et al., 2025 · Read the study ↗
Concept illustration, not study data
L-THEANINE / RANDOMIZED CROSSOVER TRIAL

Selected sleep measures.
A specific result.

In a small study of healthy adults, L-theanine improved selected self-reported sleep subscales compared with placebo, including sleep latency and disturbance.

30adults
200 mgL-theanine/day
4 weeksper intervention

The overall sleep-quality score did not significantly differ from placebo. No objective deep-sleep or REM measurement; not a trial of Rest + Restore.

Hidese et al., 2019 · Read the study ↗

These are ingredient studies, not clinical trials of Rest + Restore. They do not establish that the formula increases deep sleep, REM or treats menopausal sleep problems. Illustrations provide context and do not show study data.

THE EVENING RITUAL / REST

A daily place for winding down.

Rest + Restore Magnesium

A daily formula with magnesium, L-theanine and GABA. Pair your evening ritual with a consistent sleep schedule and a quieter wind-down routine.

325 mgElemental magnesium
200 mgL-theanine
100 mgGABA
Explore Rest + Restore ↗

A supplement is one part of an evening routine. It does not replace evaluation of persistent sleep problems.

THE EVENING RITUALHaroutine Rest and Restore Magnesium box and packet

03 + 04 / MORE OF THE BIOLOGY

Strength and clarity deserve a place.

Two distinct areas of aging well. Both have a permanent place in the protocol’s development.

MUSCLE MAINTENANCE

Muscle is continually being renewed.

Protein intake and resistance exercise provide important inputs for muscle maintenance. Responses vary with age, activity and health; reduced responsiveness is not universal.

Explore human muscle research ↗
PROTOCOL AREARecover

Physical capacity and resilience. Future formula development.

BRAIN FUNCTION

A clearer view of cognitive health.

Brain energy, communication between neurons, and sleep form distinct areas to explore. Attention and memory should be evaluated as specific outcomes.

Explore cognitive health ↗
PROTOCOL AREAThink

Cognitive health and mental clarity. Future formula development.

FROM BIOLOGY TO DAILY PRACTICE

A protocol with a purpose for each part.

Start with the available morning and evening formulas. Let the biology guide how the ritual grows.

CELLULAR ENERGY

Energize

Advanced Liposomal NMN

Explore the morning formula ↗
SLEEP & NERVOUS SYSTEM

Rest

Rest + Restore Magnesium

Explore the evening formula ↗
MUSCLE & PHYSICAL CAPACITY

Recover

Future development

Understand the biology ↗
COGNITIVE FUNCTION

Think

Future development

Understand the biology ↗

Hormonal transitions inform the context across these areas; they are not a separate hormone-treatment promise.

KOREAN DEVELOPMENT / A CLOSER LOOK AT DELIVERY

The ingredient. The formulation. The delivery.

Explore ab:MAX™ Liposomal Technology and the methods behind our validation approach.

Explore liposomal technology ↗

THE EVIDENCE, IN CONTEXT

Different questions. Different kinds of evidence.

Understanding a mechanism, testing an ingredient and validating a finished formula are separate steps.

Cellular uptake illustration: Ratajczak et al. studied the NMN → NR → cellular NMN pathway in laboratory models. Nature Communications · 2016 ↗

Concept illustration: How NAD+ reaches mitochondria.
CONTEXT ILLUSTRATION · NOT STUDY DATA
01 / CELL BIOLOGY

How NAD+ reaches mitochondria.

Luongo et al. identified SLC25A51 as a mammalian mitochondrial NAD+ transporter. Laboratory research informing the diagram, not a supplement trial.

Nature · 2020 ↗
Concept illustration: A measured change in muscle metabolism.
CONTEXT ILLUSTRATION · NOT STUDY DATA
02 / NMN INTERVENTION

A measured change in muscle metabolism.

Yoshino et al. studied 250 mg/day for 10 weeks in 25 postmenopausal women with prediabetes and overweight or obesity. Muscle insulin sensitivity improved; this does not establish the same outcome in other populations or formulas.

Science · 2021 ↗
Concept illustration: NMNAT and cellular NAD+.
CONTEXT ILLUSTRATION · NOT STUDY DATA
03 / NAD+ SYNTHESIS

NMNAT and cellular NAD+.

Ryu et al. investigated compartment-specific NAD+ synthesis in laboratory models. Useful for explaining the pathway, not proof of a consumer benefit.

Science · 2018 ↗

YOUR STARTING POINT

Your morning. Your evening. Your longevity ritual.

A little more clarity.

Does NMN turn directly into energy?

No. NMN is a precursor for NAD+. NAD+/NADH participate in metabolic reactions, while ATP is a molecule cells use to power work. The animation explains their relationship.

Does the animation show Haroutine’s product being absorbed?

No. It illustrates one studied cellular uptake route and NAD⁺ metabolism. It does not depict the complete oral absorption journey, demonstrate intact liposome delivery to mitochondria, or measure the formula’s absorption.

Are Recover and Think available products?

They are areas for future protocol development. The current starting point is Advanced Liposomal NMN and Rest + Restore Magnesium.

Does this protocol treat menopause or extend lifespan?

No such claim is made. Hormonal transitions provide educational context. The studies shown do not establish lifespan extension or hormone replacement by these formulas.